What We Do

Technology plays a vital role in the betterment of our society. Coupled with medicine, it can save countless lives while making living with chronic diseases easier. Cardiovascular diseases are a priority for us as they are globally the number 1 cause of death.

 

Congenital Heart Disease (CHD) affects approximately 40,000 (in US) and 1.3 million (globally) newborns each year. In the United States alone, the total number of patients in the affected by the CHD is now estimated to be 2.4 million patients. Of the 40,000 new patients found to have CHD each year in the US, an estimated 2,500 patients, primarily with conotruncal anomalies, have a defect that requires use of a substitute, non-native conduit artery in order to replace structures that are congenitally absent or hypoplastic. This incidence of new CHD patients and the relative distribution of defects has not changed over time and remains a function of the birth rate.

Valve and conduit replacement procedures are required for medical situations such as absence of pulmonary valve, aortic stenosis (Konno procedure, Ross procedure), double outlet right ventricle (Rastelli operation), extracardiac conduit (Fontan operation), pulmonary valve replacement (Tetralogy of Fallot). The majority of these patients will require a conduit and/or patch augmentation in the pulmonary circulation.

 

All current replacement materials have significant limitations which result in the need for multiple re-interventions, ranging from interventional catheterizations with stent implantation to multiple reoperations for conduit replacement. The limitations of these materials involve to varying degrees their thrombogenicity, durability, susceptibility to infection, and lack of growth potential.

TGen Tech’s TxGuardTM minimizes the risk factors with its innovative technology. The new TxGuardTM is regenerative (grows with children age), thrombo-resistant, calcification (plaques) resistant, infection resistant, and maintains mechanical properties. It reduces the risk of repetitive surgeries which takes off the constant financial and emotional pressure on the families making their lives easier and healthier.

 

Starting with this medical breakthrough for paediatric patients, TGen Tech is working towards expanding its horizon to help other patients suffering from various medical conditions while also creating the best possible value for our stakeholders.. We wish to make the world a better place by offering contemporary medical solutions with innovative technological assistance.